师资力量

 
 
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包文斌
发布日期:2015-03-02浏览次数:字号:[ ]

 

包文斌(1974-),男,安徽贵池人,中共党员,研究员、博士、博士生导师

通讯地址:扬州市文汇东路48号 扬州大学动物科学与技术学院

 

E—mail :wbbao@yzu.edu.cn  wenbinbao74@yahoo.com  

1.学习及工作简历

1991.9—1995.6

安徽农业大学

获学士学位

1995.9--1998.6

安徽农业大学

获硕士学位

2004.9—2007.6

扬州大学动物遗传育种专业

获博士学位

1998.8—2006.8

安徽农业大学

助教、讲师

2005.9—2006.1

作为访问学者在德国联邦农业部动物科学研究所(FAL

访问学者

2006.1—2007.8

安徽农业大学

副教授

2007.9—2012.7

扬州大学动物科学与技术学院

副教授

2012.8—

扬州大学动物科学与技术学院

研究员

2.荣誉称号和社会任职

江苏省生猪产业技术创新联盟秘书长(江苏省科技厅批准)

江苏省种猪繁育与健康养殖工程技术研究中心主任(江苏省科技厅、江苏省财政厅批准)

江苏省现代种猪分子选育工程技术研究中心主任(江苏省科技厅、江苏省财政厅批准)

江苏省规模猪场健康养殖公共技术服务中心副主任(江苏省科技厅、江苏省财政厅批准)

中国农业国际合作促进会动物福利国际合作委员会委员

江苏省畜牧业标准化技术委员会委员

2013年江苏省优秀科技特派员

2014年江苏省科技文化“三下乡活动先进个人

扬州大学优秀青年骨干教师

3. 研究方向

1)猪疾病抗性和免疫应答的分子机制

2)猪抗病育种和健康养殖

4. 科研项目及成果

 近5年来,主持或合作主持国家级和部省级科研项目17项(见清单),主持项目2007年和2008年获市级科技进步二等奖(均排名第一)、2009年获省科技进步三等奖(排名第三),授权和申请国家发明专利9项,获计算机软件著作权1项。

(1)“IncRNA—XLOC_014316和XLOC_020181对断奶仔猪大肠杆菌抗性的调控机制分析” (国家自然科学基金,31572360)主持人

(2)“miRNAs在断奶仔猪抗F18大肠杆菌感染中的作用机制分析”( 国家自然科学基金,31140027)主持人

(3)“miR-215和miR-192对断奶仔猪F18大肠杆菌抗性调控的分子机制”(国家自然科学基金,31372285)主持人

(4)“优异地方猪种种质特性的分子基础挖掘”(国家科技支撑计划,2015BAD03B01)主持人

(5)“抗仔猪腹泻病转基因猪新品系培育”(转基因生物新品种培育科技重大专项一级子课题, 2014ZX08006-001B)主持人

(6)“抗仔猪腹泻病转基因育种新材料创制”(转基因生物新品种培育科技重大专项一级子课题,2009ZX08006-004B)主持人

(7)“猪FUT1基因启动子甲基化调控大肠杆菌抗性的机制”(江苏省高校自然科学研究重大项目(A类), 14KJA230003)

(8)“家畜高效生态养殖与产业化关键技术集成创新”( 江苏省重点研发计划(现代农业)重点项目,BE2015329)合作主持人

(9)“梅山猪高产抗病新品系的选育及其杂交配套技术研究”( 江苏省产学研前瞻性联合研究项目,BY2012157)主持人

(10)“东串猪高产抗病专门化母系的分子选育”( 江苏省科技支撑计划,BE2012330)合作主持人

(11)“中梅山猪专门化母系选育及其与巴克夏猪杂交配套研究”( 江苏省科技支撑计划,BE2013345)合作主持人

(12)“江苏省现代猪种分子选育工程技术研究中心”( 江苏省科技基础设施建设计划, BM2010170)主持人

(13)“猪FUT1基因启动子区DNA甲基化修饰对大肠杆菌抗性的调控机理分析”"(教育部高等学校博士学科点专项科研基金, 20103250120006)主持人

(14)猪生产、加工和流通全过程可追溯信息化系统的研发与应用"(科技部长三角联合攻关项目,1101c0603056)主持人

(15)“多基因聚合技术培育优质抗病瘦肉型猪配套系”(江苏省科技支撑计划,BE2009330-2)合作主持人

(16)“扬州大学服务科技型养猪专业合作社科技服务专项”(江苏省科技支撑计划,BE2010450)主持人

(17)“猪健康养殖技术体系的建立与应用”(江苏省科技支撑计划,BE2008364)主持人

 

5. 发表论文

 

近5年以第一作者或通讯作者在Animal Genetics、PLos One、Gene、Int. J. Mol. Sci 、Journal of Genetics、中国农业科学、畜牧兽医学报、遗传、农业生物技术学报等国内外刊物上发表论文70余篇,其中SCI收录25篇(总影响因子44.18),权威中文期刊论文29篇。

(1) Wenhua Dong, Xuemei Yin, Li Sun, JingWang, Shouyong Sun, Guoqiang Zhu, ShenglongWu, Wenbin Bao*.Age-associated methylation change of TAP1 promoter in piglet.Gene.(SCI 收录, IF2.138)

(2) Zhengchang Wu, Riwei Xia, Xuemei Yin, YongjiuHuo, GuoqiangZhu, Shenglong Wu and Wenbin Bao*.Proteomic analysis of duodenal tissue from Escherichia coli F18-resistant and -susceptible weaned  piglets .PLos One, 2015,10(6): e0127164. (SCI 收录, IF 3.234)

(3) Z.C. Wu, Y. Liu, W.H. Dong, Y. J. Huo, S. L. Wu, W.B. Bao*. Identification of BPI protein produced in different expression system and its association with Escherichia coli F18 susceptibility. Genet Mol Res. 2015,14(1):1111-1123.(SCI 收录, IF 0.85)

(4) Z.C. Wu, Y. Liu, Q.H. Zhao, Y. J. Huo, S. L. Wu, W.B. Bao*. Association of single nucleotide polymorphisms of exon 4 and exon 10 of the BPI gene with immune indexes in Sutai pigs. Genet Mol Res. 2015,14(2):6048-6058. (SCI 收录, IF 0.85)

(5) Ying LIU, XueMei YIN, RiWei XIA, YongJiu HUO, GuoQiang ZHU, ShengLong WU, WenBin BAO*.  Association between the MUC4g.243A>G polymorphism and immune and production traits in Large White pigs. Turkish Journal of Veterinary and Animal Sciences. 2015, 39:1-6.(SCI 收录, IF0.316)

(6) S. P. Zhu, X. M. Yin, L. Sun, S. Y. Sun, W. B. Bao*, S. L. Wu*. Differential expression of porcine TAP1 gene in different populations. Russian Journal of Genetics. 2015,51(3):308-312.(SCI 收录, IF0.41)

(7) XueMei YIN, Ying LIU, WenHua DONG, QiaoHui ZHAO, GuoQiang ZHU, ShengLong WU, WenBin BAO*Association of Mx1 gene polymorphism with some economic traits in Meishan pigs. Turkish Journal of Veterinary and Animal Sciences. 2015,39: 389-394.(SCI 收录, IF0.316)

(8) Qiaohui Zhao, Ying Liu, Wenhua Dong, Shiping Zhu, Yongjiu Huo, Shenglong Wu*, Wenbin Bao*. Genetic Variations of TAP1 Gene Exon 3 Affects Gene Expression and Escherichia coli F18 Resistance in Piglets. Int. J. Mol. Sci, 2014, 15: 11161-11171. (SCI 收录, IF 2.464)

(9) Jing Wang, Xuemei Yin, Li Sun, Shouyong Sun, Chen Zi, Guoqiang Zhu, Shenglong Wu, Wenbin Bao*. Correlation between BPI Gene Upstream CpG Island Methylation and mRNA Expression in Piglets. Correlation between BPI Gene Upstream CpG Island Methylation and mRNA Expression in Piglets. Int. J. Mol. Sci, 2014, 15: 10989-10998. (SCI 收录, IF 2.464)

(10) J. Wang, Y. Liu, W.H. Dong, Y.J. Huo, X.G. Huang, S.L. Wu and W.B. Bao*. Dynamic changes in TAP1 expression levels in newborn to weaning piglets, and its association with Escherichia coli F18 resistance. Genet Mol Res. 2014, 13 (2): 3686-3692.(SCI 收录, IF 1.184)

(11) Shiping Zhu, Ying Liu, Wenhua Dong, Xianrui Zheng, Guoqiang Zhu, Shenglong Wu*, Wenbin Bao*. Polymorphism of FUT1 Gene M307 and its Relationship with Partial Immune Indexes and Economic Traits in Yorkshire Pigs[J]. Asian Journal of Animal & Veterinary Advances, 2014, 9(4): 253-261.(SCI 收录, IF 0.869)

(12) Chen Zi, Zhengchang Wu, Jing Wang, Yongjiu Huo, Guoqiang Zhu, Shenglong Wu* and Wenbin Bao*. Transcriptional Activity of the FUT1 Gene Promoter Region in Pigs[J]. Int. J. Mol. Sci, 2013, 14: 24126-24134. (SCI 收录, IF 2.464)

(13) Wang J, Pan ZY, Zheng XR, Wu ZC, Su XM, Zhu GQ, Huang XG, Wu SL*, Bao WB*. TLR4 gene expression in pig populations and its association with resistance to Escherichia coli F18. Genet Mol Res, 2013, 12(3):2625-2632. (SCI 收录, IF 1.184)

(14) Lu Liu, Jing Wang, Qiaohui Zhao, Chen Zi, Zhengchang Wu, Xianmin Su a, Yongjiu Huo, Guoqiang Zhu, Shenglong Wu*, Wenbin Bao*. Genetic variation in exon 10 of the BPI gene is associated with Escherichia coli F18 susceptibility in Sutai piglets. Gene, 2013, 523(1): 70-75. (SCI 收录, IF 2.266)

(15) J. Zhu, C. Zi, Z.C. Wu, L. Liu, X.R. Zheng, X.M. Su, G.Q. Zhu, X.G. Huang, S.L. Wu* and W.B. Bao*. Age-dependent expression of the BPI gene in Sutai piglets[J]. Genet Mol Res, 2013, 12(2): 2120-2126. (SCI 收录, IF 1.184)

(16) L. Ye, C. Zi, Z.Y. Pan, J. Zhu, Z.D. Du, G.Q. Zhu, X.G. Huang, W.B. Bao*, S.L. Wu*. Investigation of the relationship between SLA-1 and SLA-3 gene expression and susceptibility to Escherichia coli F18 in post-weaning pigs. Comparative Immunology, Microbiology and Infectious Diseases, 2012 (35): 23–30. (SCI 收录, IF 3.605)

(17) Lan Ye, Xianmin Su, Zhengchang Wu, Xianrui Zheng, Jin Wang, Chen Zi, Guoqiang Zhu, Shenglong Wu*, Wenbin Bao*. Analysis of Differential miRNA Expression in theDuodenum of Escherichia coli F18-Sensitive and -Resistant Weaned Piglets. PLoS ONE, 7(8): e43741. (SCI 收录, IF 4.411)

(18) Wen-bin Bao, Lan Ye, Chen Zi, Lu Liu, Chen Zi, Jing Zhu, Zhang-yuan Pan, Guo-qiang Zhu, Xue-gen Huang, Sheng-long Wu*. Relationship between the expression level of SLA-DQA and Escherichia coli F18 infection in piglets. Gene, 2012 (494): 140–144. (SCI 收录, IF 2.341)

(19) Wen-Bin Bao, Lan Ye, Chen Zi, Xian-Min Su, Zhang-Yuan Pan, Jin Zhu, Guo-Qiang Zhu, Xiao-Guo Huang, Sheng-Long Wu*. Study on the age-dependent tissue expression of FUT1 gene in porcine and its relationship to E. Coli F18 receptor, Gene, 2012 (497): 336–339. (SCI 收录, IF 2.266)

(20) Wen-bin Bao, Lan Ye, Zhang-yuan Pan, Jing Zhu, Zi-Dong Du, Guo-qiang Zhu, Xue-gen Huang,  Sheng-long Wu*. The effect of mutation at M307 in FUT1 gene on susceptibility of Escherichia coli F18 and gene expression Sutai piglets. Molecular Biology Reports, 2012, 39(3): 3131–3136. (SCI 收录, IF 2. 922)

(21) Wen-bin Bao, Lan Ye, Jing Zhu, Zhang-yuan Pan, Guo-qiang Zhu, Xue-gen Huang, Sheng-long Wu*. Evaluation of M307 of FUT1 gene as a genetic marker for disease resistance breeding of Sutai pigs. Molecular Biology Reports, 2012, 39(4): 4223–4228. (SCI 收录, IF 2. 922)

(22) W. B. Bao, L. Ye, Z. Y. Pan, J. Zhu, Z. D. Du, G. Q. Zhu, X. G. Huang and S. L. Wu*. Microarray   analysis of differential gene expression in sensitive and resistant pig to Escherichia coli F18. Animal Genetics, 2012, 43(5): 525-534.(SCI 收录, IF 2.403)

(23) W. B. BAO, L. YE, Z. Y. PAN, J. ZhU, G. Q. ZhU, X. G. HUANG, S. L.WU*. Analysis  of  polymorphism in the porcine TLR4 gene and its expression related to Escherichia coli F18 infection. Czech Journal of Animal Science, 2011, 56(11): 475–482.(SCI 收录, IF 1.190)

(24) W. B. Bao, L. Ye, J. Zhu, Z. Y. Pan, G. Q. Zhu, X. G. Huang & S. L. Wu*. Beneficial genotype of swine FUT1 gene governing resistance to E. coli F18 is associated with important economic traits. Journal of Genetics, 2011, 90(2): 315–318. (SCI 收录, IF 1.338)

(25) WEN-Bin Bao, Lan Ye, ZHANG-Yuan Pan, Jin Zhu, GUO-Qiang Zhu, XUE-Gen Huang and SHENG-Long Wu*. Polymorphism of M307 of the FUT1 gene and its relationship with some immune indexes in Sutai pigs (Duroc × Meishan). Biochemical Genetics, 2011, 49: 665–673. (SCI 收录, IF 0.825)

6. 教学工作及主要成绩

主讲研究生《生物信息学》

主编《猪标准化生产技能操作教程》,参编《中国养猪大成》、《动物遗传学》等著作和教材3

 

 

 

 

 

 

 

 

 

 




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