Lecture : Gene therapy

Reporter：Zoltán Ivics 教授 院士

单位：德国PEI研究所

时间：2021年11月23日，晚上8：30

课程负责人：高波 教授

线上报告：腾讯会议号：7983276331

Prof. Dr. Zoltán Ivics, Head of Division, Medical Biotechnology, Paul Ehrlich Institute

Zoltán Ivics received his PhD in molecular biology in 1994. After postdoctoral studies at the University of Minnesota in the USA and the Netherlands Cancer Institute, he was appointed as a research group leader at the Max Delbrück Center for Molecular Medicine in Berlin, Germany. He was appointed as Head of Division at the Paul Ehrlich Institute in Langen, Germany, in 2011. Prof. Ivics’ major scientific achievement is the molecular reconstruction of the Sleeping Beauty transposon and development of technologies based on Sleeping Beauty gene transfer for a wide array of applications involving genetic engineering of cells. Prof. Ivics has published >150 papers in peer reviewed journals, with a total Impact Factor of >1200 and >8000 citations (h-index: 48 by Scopus), and is co-inventor on 12 patents. Since 2000 his research efforts were supported by 23 research grants from the German Research Foundation, the German Ministry of Education and Research, the European Commission, and the Volkswagen Foundation. He received recognition of the “Molecule of the Year” in 2009 for developing a hyperactive Sleeping Beauty transposase that opened the door for clinical applications. He is a current member of the Board of the European Society of Gene and Cell Therapy (ESGCT), member of the Board of the German Society of Gene Therapy and member of the committee for “Clinical trials and regulatory affairs” of the German Stem Cell Network. Prof. Ivics organized several international conferences, including the Annual Congress of the ESGCT in Berlin in 2017. He is an Elected Member of the Academia Europaea since 2018.

Zoltán Ivics教授，欧洲科学院院士，Paul Ehrlich研究所负责人

Zoltán Ivics于1994年获得分子生物学博士学位。先后在美国明尼苏达大学和荷兰癌症研究所开展博士后研究工作，之后被任命为德国柏林Max Delbrück分子医学中心的研究组组长。于2011年，被任命为德国朗根Paul Ehrlich研究所的负责人。Ivics教授的重要科学成就之一就是对睡美人转座子（Sleeping Beauty，SB）的分子重建和基于睡美人转座子进行的基因转移的技术开发以及在细胞基因工程中的应用。Ivics教授发表论文超过150篇，总影响因子超过1200，引用次数超过8000次（H 指数：Scopus 为 48），并且是12项专利的共同发明人。自2000年以来，他的研究工作得到了德国研究基金会、德国教育和研究部、欧盟委员会和大众汽车基金会的23项研究资助。他开发的可应用于临床应用的活跃睡美人转座酶在2009年获得了“年度最佳分子”的称号。他是欧洲基因和细胞治疗协会(ESGCT)的现任董事会成员、德国基因治疗协会的董事会成员以及德国干细胞“临床试验和监管事务”委员会的成员。Ivics教授组织了多次国际会议，包括2017年在柏林举行的ESGCT年度大会。2018年当选为欧洲科学院院士。